
产品货号:
Z33049
中文名称:
AKT1抗体
英文名称:
Anti-AKT1 Antibody (Clone#2D9-D2-H3)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-AKT1 Antibody (Clone#2D9-D2-H3) |
指标别名 | AKT;AKT1;PKB;PKB ALPHA;PRKBA;Protein kinase B;Proto oncogene c Akt;RAC;RAC ALPHA;RAC PK alpha |
克隆性 | Monoclonal |
检验物种 | mouse |
应用范围 | WB,ELISA |
基因名称 | akt1 |
克隆号 | 2D9-D2-H3 |
抗体来源 | Mouse |
抗体类型 | IgG |
免疫原 | Purified recombinant human AKT1 protein fragments expressed in E.coli. |
计算分子量 | 65KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | RAC-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene.The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts.AKT1 and the related AKT2 are activated by platelet-derived growth factor.The activation is rapid and specific,and it is abrogated by mutations in the pleckstrin homology domain of AKT1.It was shown that the activation occurs through phosphatidylinositol 3-kinase.In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival.Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1,which then phosphorylates and inactivates components of the apoptotic machinery.Mutations in this gene have been associated with the Proteus syndrome.Multiple alternatively spliced transcript variants have been found for this gene. |
Uniprot ID | P31749 |
基因名全称 | PX domain-containing protein kinase-like protein |
蛋白名全称 | PX domain-containing protein kinase-like protein |
推荐稀释比 | WB 1:500~2000 ELISA 1:10000~20000 |
相关搜索:AKT1抗体,AKT1单抗,Anti-AKT1 Antibody (Clone#2D9-D2-H3)